The Centre for Infectious Disease Genomics and One Health at SFU is an interdisciplinary group of researchers with backgrounds in microbiology, molecular biology, computer science, cognitive science, statistics, public health, and genomics. We are interested in solving practical health problems using multidisciplinary approaches and in a One Health framework. Our research combines knowledge engineering techniques (e.g. ontology modeling, data curation, semantic web), bioinformatics tools (e.g.genomic sequence analysis, phylogenetic, comparative genomics, text mining, workflow and platform development) and molecular laboratory experiments (microbial genomics, metagenomics, eDNA, and virome) to understand the impact of infectious diseases on human and animal health. Given the diversity of microorganisms (bacteria, viruses, parasites) and the complex of biological phenomena that we seek to understand, data-driven research in microbiology requires researchers to collaborate and to share data. Developing technologies to foster data harmonization and sharing, and building trusted networks of health care practitioners, researchers, and policy makers are therefore key focuses of the Centre. We are interested in working with partners to generate data, to analyze data, and to share (and re-use) data for the broader benefit of the scientific community. Our facility includes a state-of-the-art molecular laboratory for microbial sample processing and omics data generation and access to high-performance computing clusters and cloud computing (courtesy of Compute Canada) to provide a “one-stop-shop” for research and collaboration.